ISSN 2398-2950      

Frunevetmab

ffelis
Contributor(s):

Jo Murrell

Matasaka Enomoto

Synonym(s): Solensia, a felinized monoclonal antibody


Introduction

Name

  • Frunevetmab.

Class of drug

  • Felinized monoclonal antibody to nerve growth factor (NGF). 

Description

Storage requirements

  • Store in a fridge (2-8°C), protect from light. Do not shake the solution to induce foaming or frothing. 

Uses

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Indications

Administration

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Pharmacokinetics

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Precautions

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Interactions

With other drugs

  • There are no safety data on the long term use of frunevetmab with long term NSAID administration. A phenomenon called rapidly progressive osteoarthritis has been reported in humans given humanized anti-nerve growth factor antibody, particularly when administered concurrently with long term NSAIDs. An equivalent disease to rapidly progressive osteoarthritis is not reported to occur in cats.

With diagnostic tests

  • No known interactions. 

Adverse Reactions

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Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMedResource.
  • Enomoto M, Mantyh P W, Murrell J, Innes J F, Lascelles B D X (2019) Anti-nerve growth factor monoclonal antibodies for the control of pain in dogs and cats. Vet Rec 184(1), 23 PubMed.

Other sources of information

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk
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