Introduction

Name

• Acetyl salicylic acid.

Class of drug

• Non-steroidal anti-inflammatory drug (NSAID).

Description

Chemical name

• 2-(acetyloxy)benzoic acid.
• Salicylic acid acetate.

Molecular formula

• C9H8O4.

Physical properties

• Tablets.

Storage requirements

• In a cool, dry place.

Uses

Indications

• Control of mild to moderate pain Pain: management. Use has been largely superceded by licensed NSAIDs.
• Prevention of arterial thromboembolization Thromboembolism: aorta.
• Rheumatoid arthritis Arthritis: rheumatoid.

Administration

Pharmacokinetics

Precautions

Interactions

with other drugs

• Do not use with corticosteroids, methoxyflurane Methoxyflurane or other NSAIDs.
• In man there is an increased risk of convulsions if NSAIDs are administered with fluoroquinolones.
• NSAIDs may antagonize the hypotensive effects of anti-hypertensives, eg beta-blockers.
• Concomitant use of diuretics may increase the risk of nephrotoxicity.
• Do not mix with other substances in the same syringe.

Adverse Reactions

Further Reading

Publications

Refereed papers

• Recent references from PubMed and VetMedResource.

Other sources of information

• Based on Small Animal Formulary. Tennant, Bryn (1999) 3rd edn. BSAVA, UK.