Introduction

Name

• Oxfendazole.

Class of drug

• Benzimidazole anthelmintic.

Description

Chemical name

• 5-(phenylsulfinyl)-1H-benzimidazol-2-ylcarbamic acid methyl ester.

Molecular formula

• C₁₅H₁₃N₃O3S.

Molecular weight

• 315.3.

Physical properties

• White or almost white powder possessing a characteristic odor.
• It is practically insoluble in water.

Storage requirements

• Store in a dry environment at room temperature.

Uses

Indications

• Infestations with ascarids, oxyurids, lungworms, other nematodes and some cestodes.
• Faster effect than fenbendazole (12 days vs 31 days in tortoises).

Administration

Pharmacokinetics

Adverse Reactions

Further Reading

Publications

Refereed papers

• Recent references from PubMed and VetMedResource.
• Manire C A, Kinsel M J, Anderson E T et al (2008) Lungworm infection in three loggerhead sea turtles, Caretta caretta. J Zoo Wildl Med 39 (1), 92-98.

• Giannetto S, Brianti E, Poglayen G et al (2007) Efficacy of oxfendazole and fenbendazole against tortoise (Testudo hermanni) oxyurids. Parasitol Res 100 (5), 1069-1073.

Other sources of information

• Plumb D (2015) Plumb’s Veterinary Drug Handbook. 8th edn. Wiley-Blackwell. pp 1296.
• McArthur S, Wilkinson R & Meyer J (2004) Medicine and Surgery of Tortoises and Turtles. Blackwell Publishing, UK. pp 579.
• Tennant B (1999) Small Animal Formulary. 3rd edn. BSAVA, UK.

Organisation(s)

• National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.