ISSN 2398-2985      

Urinalysis: bilirubin

6guinea pig


Overview

  • Only conjugated bilirubin appears in urine (unconjugated is albumin bound).
  • Bilirubin blood levels are often indicative of hepatocellular and biliary system function. Kidneys can excrete large amounts and elevations usually indicative of biliary obstruction or severe renal compromise.
  • Rabbits are unlikely to have increased levels of bilirubin in their urine because they rarely have increased levels of circulating bilirubin as they produce biliverdin as the predominant heme metabolite. Data are lacking to confirm that it is the same for guinea pigs.

Sampling

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Tests

Methodologies

  • Mix the urine specimen thoroughly.
  • Pipette urine onto test pads.
  • Hold horizontally to avoid run-off between pads.
  • Read test at correct interval.
  • Sediment examination may reveal bilirubin crystals (rare).

Availability

  • All veterinary practices.
  • External laboratories.

Result Data

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Further Reading

Publications

Refereed papers

Other sources of information

  • Quesenberry K E, Donnelly T M & Mans C (2012) Biology, Husbandry and Clinical Techniques of Guinea Pigs and Chinchillas. In: Ferrets, Rabbits and Rodents Clinical Medicine and Surgery. Eds: Quesenberry K E & Carpenter J W. Elsevier Saunders, St. Louis, MO. pp 279-294.
  • Oglesbee B L (2011) Blackwells Five-Minute Veterinary Consult: Small Mammal. 2nd edn. Wiley-Blackwell, USA.
  • Wesche P (2009) Rodents: Clinical Pathology. In: BSAVA Manual of ferrets and rodents. Eds: Keeble E & Meredith A. British Small Animal Veterinary Association, UK. pp 42-51.

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