ISSN 2398-2985      

Amitraz

6guinea pig

Synonym(s): Aludex, Promeris Duo, Mitaban


Introduction

Name

  • Amitraz.

Class of drug

  • Diamide topical antiparasitic agent.

Description

Molecular formula

  • N’-(2,4-dimethylphenyl)-N-[[2,4-dimethylphenyl)imino]methyl]-N-methyl-methylmethanimidamide.

Physical properties

  • Pale yellow, sparingly soluble in water but soluble in most organic solvents. Relatively stable to heat.

Storage requirements

  • Do not store diluted product.

Uses

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Indications

  • Used to treat generalized mite infestations including demodicosis, sarcoptes, cheyletiellosis and ticks (amitraz collar).
  • Amitraz use has decreased as newer and safer antiparasitic drugs, eg avermectins, have developed.

Administration

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Pharmacokinetics

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Precautions

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Interactions

with other drugs

  • Do not give with monoamineoxidase inhibitors, eg hydroxyzine, or other tricyclic antidepressants (clomipramine, amitriptyline).

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Duncan K L (1993) Treatment of amitraz toxicosis. JAVMA 203 (8), 1115-1116 PubMed.
  • Michels G (1993) Treatment of amitraz toxicosis. JAVMA 203 (8), 1116 PubMed.

Other sources of information

  • Meredith A (2015) Ed BSAVA Small Animal Formulary. Part B: Exotic Pets. 9th edn. BSAVA, UK. pp 338.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.
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