ISSN 2398-2985      

Gastritis

6guinea pig

Synonym(s): Inflammation of the gastric mucosa


Introduction

  • Cause: inflammation of the gastric mucosa. Acute or chronic.
  • Signs: anorexia, hypersalivation, tooth grinding, weight loss, melena (if gastric ulceration present).
  • Diagnosis: clinical presentation, radiographs, contrast radiographs, gastroscopy, gastric lavage, biopsy, PCR, fecal parasitology, post-mortem findings.
  • Treatment: supportive care with fluid therapy, analgesia, nutritional support. Gastric protectants, antacids. Targeted treatment of the inciting cause.
  • Prognosis: good to guarded depending on the etiology.

Pathogenesis

Etiology

  • Multiple possible etiologies for acute and chronic gastritis.
  • Gastric ulceration Gastric ulceration.
  • Helicobacter pylori.
  • Poor husbandry.
  • Chronic stress may be associated with gastric ulceration.
  • Effects of drugs, eg corticosteroids, NSAIDs.

Predisposing factors

General

  • Poor husbandry.
  • Stress.
  • Immunosuppression.
  • Poor housing hygiene.

Specific

  • Use of corticosteroids or NSAIDs may lead to gastric ulceration.

Pathophysiology

  • Inflammation of the gastric mucosa.

Timecourse

  • Acute or chronic presentation.

Epidemiology

  • May see outbreaks of disease in groups, eg parasitic infections.

Diagnosis

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Treatment

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Prevention

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Outcomes

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Further Reading

Publications

Refereed Papers

Other sources of information

  • Hoefer H L, Fox J G & Bell J A (2012) Gastrointestinal Diseases. In: Ferrets, Rabbits and Rodents. 3rd edn. Eds: Quesenberry K E & Carpenter J W. Elsevier, USA. pp 27-45.

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