ISSN 2398-2985      

Blood biochemistry: gammaglutamyl transferase

4ferrets

Synonym(s): GGT, Gammaglutamyl transpeptidase, ⍺-Glutaryltransferase


Overview

  • Gammaglutamyl transferase (GGT) is a membrane-associated enzyme, produced in liver, pancreas and kidney.
  • Liver GGT is found primarily in the epithelium of the bile ducts.
  • The hepatobiliary system is therefore the primary source of serum GGT and is more diagnostic for hepatobiliary disease than for hepatocellular damage.
  • In addition to biliary GGT, which is the main source of GGT, significant levels of renal epithelial GGT can be found in the urine.
  • Urine GGT levels may be increased in cases of renal damage; in addition, plasma GGT may also be increased in these cases, but this is rare.

Sampling

This article is available in full to registered subscribers

Sign up now to start a free trial to access all Vetlexicon articles, images, sounds and videos, or Login

Tests

Methodologies

  • Varies between laboratories, usually colorimetric method based on enzymatic reaction.

Availability

  • Widely available.

Validity

Predictive value

Technique (intrinsic) limitations

  • Test results most significant in conjunction with other laboratory results and clinical findings.

Result Data

This article is available in full to registered subscribers

Sign up now to start a free trial to access all Vetlexicon articles, images, sounds and videos, or Login

Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMedResource.
  • Hein J, Spreyer F, Sauter-Louis C et al (2012) Reference ranges for laboratory parameters in ferrets. Vet Rec 171, 218 PubMed.
  • Hauptman K, Tichy F & Znotek Z (2001) Clinical diagnostics of hepatopathies in small mammals: evaluation of importance of individual methods. Acta Vet Brno 70, 297-311.

Other sources of information

  • Phelps C A & Mayer J (2013) Gammaglutamyl Transferase. In: Clinical Veterinary Advisor Birds and Exotic Pets. Eds: Mayer J & Donnelly T M. Eslevier, USA. pp 617-618.

MEMBER BENEFIT

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code