ISSN 2398-2985      

Finasteride

4ferrets

Synonym(s): Proscar, Propecia


Introduction

Name

  • Finasteride

Class of drug

  • Anti-androgen.
  • 5-alpha reductase inhibitor.

Description

Chemical name

  • (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide.

Molecular formula

  • C23H36N2O2.

Molecular weight

  • 372.55.

Physical properties

  • White/off white crystalline solid.

Storage requirements

  • Store tablets at temperatures below 30°C/86°F, in tight containers and protected from light.

Uses

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Indications

  • Benign prostatic hyperplasia and other prostatic abnormalities secondary to adrenal disease.
  • Finasteride is relatively expensive and requires long duration of therapy: limited use in veterinary medicine.
  • Anecdotal use in ferrets. Proper studies on dosages and efficacy have not been performed.
  • It should be used in males only.

Administration

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Pharmacokinetics

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Precautions

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Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Meredith A (2015) Ed. Small Animal Formulary. Part B: Exotic Pets. 9th edn. BSAVA, Quedgeley, UK. pp 338.
  • Fox J G & Marini R P (2014) Biology and Diseases of the Ferret. 3rd ed. Wiley Blackwell, USA. pp 835.
  • Mayer J & Donnelly T M (2013) Clinical Veterinary Advisor: Birds and Exotic Pets. Elsevier, USA. pp 752.
  • Plumb D C (2008) Plumb's Veterinary Drug Handbook. 6th edn. Blackwell Publishing, USA. pp 1120.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.
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