ISSN 2398-2985      

Clarithromycin

4ferrets

Synonym(s): Kalricid


Introduction

Name

  • Clarithromycin.

Class of drug

  • Macrolide antibiotic.

Description

Chemical name

  • 6-O-Methylerythromycin.

Molecular formula

  • C38H69NO13.

Molecular weight

  • 747.96.

Physical properties

  • White to off-white crystalline powder.
  • Practically insoluble in water, slightly soluble in ethanol, and soluble in acetone

Storage requirements

  • Store at room temperature, in well-closed containers and protected from light.
  • After reconstiting the oral solution, it should be stored at room temperature and discard after 14 days.
Do not refrigerate.

Uses

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Indications

  • Useful for treating Helicobacter infection and atypical mycobacteriosis in ferrets.
  • Alternative to penicillin in penicillin-allergic individuals.
  • Treatment of respiratory tract infections, mild to moderate skin and soft tissue infections.

Administration

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Pharmacokinetics

Precautions

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Interactions

with other drugs

Methylprednisolone, theophylline
  • Increased serum levels of these drugs.
Digoxin
  • Enhanced absorption of digoxin.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Meredith A (2015) Ed. BSAVA Small Animal Formulary. Part B: Exotic Pets. 9th edn. BSAVA, Quedgeley, UK. pp 338.
  • Plumb D C (2008) Plumb's Veterinary Drug Handbook. 6th edn. Blackwell Publishing, USA. pp 1120.
  • Tennant B (1999) Small Animal Formulary. 3rd edn. BSAVA, UK.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.
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