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Prostatic disease


Introduction

  • Cause: prostate enlargement is part of the adrenal disease complex.
  • Signs: stranguria, dysuria, distended bladder, inability to urinate, pain on palpation.
  • Diagnosis: ultrasonography, radiography.
  • Treatment: drainage of large cysts, restore urine flow with relaxant, urethral catheterization.
  • Prognosis: guarded.

Presenting signs

  • Stranguria.
  • Dysuria.
  • Distended bladder.
  • Inability to urinate.
  • Pain on palpation of pelvic area.
  • Other clinical signs associated with adrenal disease, eg symmetrical alopecia Alopecia.

Age predisposition

  • As adrenal disease occurs generally in ferrets over 3 years old, prostatic disease also occurs in ferrets older than 3 years old.

Pathogenesis

Etiology

  • Adrenal disease is associated with elevated circulating sexual hormones, which stimulate squamous metaplasia of prostatic tissue.
  • Prostate may be cystic or hypertrophic or a combination of both.
  • Cysts are usually sterile, but they can develop into bacterial abscesses.
  • Urethra may be compressed making it difficult to void:
    • In severe cases the urethra is blocked completely.
    • The urethra may be blocked internally with prostate cells and secretions, or it may be compressed by the prostate tissue.
  • Secondary cystitis Cystitis and urolithiasis and atonic bladder may be present.
  • This condition can be life-threatening if urine flow is not restored.
  • Prostatic disease unrelated to adrenal disease is rare in ferrets.

Diagnosis

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Treatment

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Prevention

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Powers L V, Winkler K, Garner M et al (2007) Omentalization of prostatic abscesses and large cysts in ferrets (Mustela putorius furo). J Exotic Pet Med 16 (3), 186-194 VetMedResource.

Other sources of information

  • Mayer J & Donnelly T M (2013) Clinical Veterinary Advisor: Birds and Exotic Pets. Elsevier, USA. pp 752.