ISSN 2398-2985      

Hypothyroidism

4ferrets

Introduction

  • Cause: unknown.
  • Signs: obesity, lethargy, hindlimb weakness.
  • Diagnosis: TSH stimulation testing.
  • Treatment: oral treatment with levothyroxine.
  • Prognosis: excellent with treatment;
  • Hypothyroidism is characterized by impaired production or secretion of thyroid hormones by the thyroid gland, resulting in a decreased concentration of circulating thyroid hormone and associated clinical signs.
  • Although the disease is one of the most common endocrine diseases seen in dogs, hypothyroidism has only rarely been described in ferrets.

Pathogenesis

Etiology

  • Currently not known.
  • In dogs, primary hypothyroidism, resulting from either immune-mediated lymphocytic thyroiditis or idiopathic thyroid atrophy, is most common. On rare occasions, primary or metastatic neoplasia may also cause hypothyroidism. In cats, hypothyroidism is most commonly iatrogenic, resulting from treatment for hyperthyroidism.

Pathophysiology

  • Currently not known.

Epidemiology

  • Hypothyroidism and hyperthyroidism are rare and poorly described in ferrets.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

Other sources of information

  • Schoemaker N J & van Zeeland Y R A (2017) Disorders of the Endocrine System. In: Ferret Medicine and Surgery. Ed: Johnson-Delaney C A. CRC Press, USA. pp 191-218.
  • Miller C M, Marini R P & Fox J G (2014) Diseases of the Endocrine System. In: Biology and Diseases of the Ferret. 3rd edn. Eds: Fox J G & Marini R P. Wiley Blackwell, USA. pp 377-400.
  • Rosenthal K L & Wyre N R (2012) Endocrine Diseases. In: Ferrets, Rabbits and Rodents: Clinical Medicine and Surgery. 3rd edn. Eds: Quesenberry K E & Carpenter J W. Elsevier, USA. pp 86-102.
  • Wagner R A (2012) Hypothyroidism in Ferrets. In: Proceedings of the Annual Conference of the Association of Exotic Mammal Veterinarians. Oakland, CA, USA. pp 29-32.

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