Dinoprost tromethamine
Introduction
Name
- Dinoprost tromethamine.
Class of drug
- Prostaglandin.
- Prostaglandin F2α (PGF2α).
Description
Chemical name
- 2-amino-2-(hydroxymethyl)propane-1,3-diol.
Molecular formula
- C20H34O5.C4H11NO3; C24H45NO8.
Molecular weight
- 475.62.
Physical properties
- Supplied as a clear, aqueous solution for injection.
Uses
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Administration
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Pharmacokinetics
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Precautions
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Withdrawal Periods
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Adverse Reactions
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Barker K J, Mateu Sánchez S, Serrano Y R, Lacey F M & Crabtree J R (2019) Prostaglandin F2 alpha-induced maternal behaviour for fostering orphan foals and for mares demonstrating foal rejection. Equine Vet J 61, S53.
- Holland B & Pinto C R F (2008) Luteal function and ovulation in mares treated with PGF2a during early and mid-diestrus. Reprod Domest Anim 43 (Suppl 3), 111 Wiley.
- Barker C, Echeverria K & Davis M (2006) Effects of different doses of PGF2 on luteal function and on the subsequent estrous cycle. Anim Reprod Sci 94, 207–209.
- Bergfelt D R, Pierson R A & Ginther O J (2006) Regression and resurgence of the CL following PGF2alpha treatment 3 days after ovulation in mares. Theriogenology 65 (8), 1605-1619 PubMed.
- Klem M E Jr, Kreider J L, Harms P G, Potter G D, Kraemer D C & Godke R A (1982) Induction of parturition in the mare with prostaglandin F2 alpha. Prostaglandins 24 (1), 89-96 PubMed.
Other sources of information
- Staempfli S A (2011) Pharmacologic Manipulation of Reproduction: Prostaglandins. In: Equine Reproduction. 2nd edn. Eds: McKinnon A O, Squires E L, Vaala W E & Varner D D. Wiley-Blackwell. pp 1797-1804.
- The NOAH Compendium of datasheets of licensed veterinary medicines. Available at: https://www.noahcompendium.co.uk.
- Veterinary Medicines Directorate. Adverse Reaction Reporting. Available at: https://www.vmd.defra.gov.uk.
- Veterinary Medicines Directorate. Questions and Answers on FDA's Adverse Event Reporting System (FAERS). Available at: https://www.fda.gov/drugs.