ISSN 2398-2977      

Cisplatin

pequis
Contributor(s):

Vetstream Ltd

Anna Hollis


Introduction

Name

  • Cisplatin.

Class of drug

Description

Chemical name

  • (SP-4-2)-diamminedichloridoplatinum(II).

Molecular formula

  • Cl2H6N2Pt.

Molecular weight

  • 300.05 g/mol.

Storage requirements

  • 15-25°C/59-77°F.
  • Do not refrigerate.
  • Protect from light.

Uses

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Indications

Administration

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Precautions

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Interactions

With other drugs

  • Aminoglycosides increase risk of nephrotoxicity, ototoxicity.

Adverse Reactions

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Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMedResource.
  • Theon A P, Pascoe J R, Carlson G P & Krag D N (1993) Intratumoral chemotherapy with cisplatin in oily emulsion in horses. JAVMA 202 (2), 261-267 PubMed.

Other sources of information

  • Theon A P, Galuppo L D, Snyder J R & Wilson W D (2006) Intratumoural administration of cisplatin for treatment of sarcoids in 378 horses. In: Proc AAEP Conference. Vol 52. pp 337-339.
  • Goodrich L R & Semevolos S A (2000) How to prepare and inject cisplatin in oily emulsion to treat equine sarcoids and squamous cell carcinomas. In: Proc AAEP Conference. Vol 46. pp 173-175.
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