Introduction

Name

• Acepromazine.

Class of drug

• Phenothiazine sedative.

Description

Chemical name

• 1-[10-[3-(dimethylamino)propyl]-10H-phenothiazin-2-yl]ethanone.
• 10-[3-(dimethylamino)propyl]phenothiazin-2-yl methyl ketone.

Molecular formula

• C19H22N2OS.C4H4O4.

Physical properties

• Pale yellow injectable solution, gel or tablets.

Tablets are not licensed for use in horses in the UK.

Storage requirements

• <25°C.

Uses

Indications

• Pre-anesthetic medication.
• Sedation.

Administration

Precautions

Adverse Reactions

Further Reading

Publications

Refereed papers

• Recent references from PubMed and VetMedResource.
• Driessen B, Zarucco L, Kalir B & Bertolotti L (2011) Contemporary use of acepromazine in the anaesthetic management of male horses and ponies: A retrospective study and opinion poll. Equine Vet J 43 (1), 88-98 PubMed. 
• Menzies-Gow N J (2008) Effects of sedation with acepromazine on echocardiographic measurements in eight healthy thoroughbred horses.Vet Rec 163 (1), 21-25 PubMed.

Other sources of information

• Derived from The Veterinary Formulary (2001) 5th edn. Ed: Bishop Y. British Veterinary Association and Royal Pharmaceutical Society.