ISSN 2398-2977      

Adnexal lymphoma

pequis
Contributor(s):

Anna Hollis

Katie Snalune


Introduction

  • Cause: the adnexa is rarely the primary or sole site of lymphoma, and diagnosis of ocular or periocular lymphoma is more likely to be the manifestation of multicentric or disseminated disease.
  • Signs: usually involves the adnexa but may also occur in conjunctiva, uvea, cornea, sclera, or retrobulbar space. Eyelid infiltration and involvement of the conjunctiva and nictitans is the most common form of ocular lymphoma. Orbital forms are usually part of multicentric lymphoma. Clinical signs depend on location of lesion, but swelling, nodular lesions, and hyperemia are common.
  • Diagnosis: biopsy.
  • Treatment: solitary lymphoma lesions may be successfully treated via wide surgical excision or radiotherapy. Multicentric lymphoma may be treated with chemotherapy or corticosteroids, but this is usually palliative in nature.
  • Prognosis: solitary lymphoma can have a good prognosis if found and treated at an early stage. The prognosis is poor for multicentric lymphoma or lesions that have a late diagnosis.

Pathogenesis

Etiology

  • May be part of multicentric disease; in one report 27% of horses with multicentric lymphoma Lymphosarcoma: overview presented with ocular involvement.
  • May be a solitary lesion.

Timecourse

  • Variable timecourse; may present with insidious onset or more acutely.

Diagnosis

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Treatment

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Outcomes

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMedResource.
  • Martabeno B B, Brooks D E, Whitley R D et al (2019) Recurrent adnexal lymphoma in a horse. Equine Vet Educ 31 (4), 203-207 WileyOnline.
  • Schnoke A T, Brookes D E, Wilkie D A et al (2013) Extraocular lymphoma in the horse. Vet Ophthalmol 16 (1), 35-42 PubMed.
  • Rebhun W C (1998) Tumors of the eye and ocular adnexal tissues. Vet Clin North Am Equine Pract 14 (3), 579-606 PubMed.

Other sources of information

  • Gelatt K N, Ben-Shlomo G, Gilger B C, Hendrix D V H, Kern T J & Plummer C E (2021) Eds Veterinary Ophthalmology. Wiley-Blackwell, USA. ISBN: 9781119441830.
  • Knottenbelt D, Patterson-Kane J C & Snalune K (2013) Eds Clinical Equine Oncology. Elsevier, UK. ISBN: 9780702042669.

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code