Hematology: mean corpuscular hemoglobin concentration
Synonym(s): MCHC
Overview
- More accurate measure of hemoglobin in red blood cells than mean corpuscular hemoglobin (MCH) Hematology: mean corpuscular hemoglobin.
Uses
In combination
- With RBC indices in investigation and monitoring of anemia Anemia: overview.
Sampling
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Tests
Methodologies
- MCHC = Hb Hematology: hemoglobin concentration (g/l) divided by PCV Hematology: packed cell volume (l/l).
- Rough estimation of MCHC can be made on examination of a blood smear.
Availability
- Widely available at commercial laboratories.
Validity
Sensitivity
- Low.
Specificity
- Low.
Technique intrinsic limitations
- Represents mean values only (Hb change in small numbers of RBCs can be detected by visual assessment of pigmentation on stained blood smear).
Result Data
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Further Reading
Publications
Refereed papers
- Recent references from VetMedResource and PubMed.
Other sources of information
- Cowell R L, Tyler R D & Meinkoth J H (1999) Diagnostic Cytology and Hematology of the Dog and Cat. 2nd edn. Mosby, USA.
- Duncan J R, Prasse K W & Mahaffy E A (1994) Veterinary Laboratory Medicine Clinical Pathology. 3rd edn. Iowa University Press, Ames, USA.
- Jain N C (1993) Essentials of Veterinary Hematology. Lea & Febiger, USA.