Overview

• Produced in liver - major component of total plasma protein Blood biochemistry: total protein Blood biochemistry: total globulin.
• Relative and absolute changes in plasma levels occur with a variety of disease processes.
• More useful in combination with total protein measurement.
• Half-life of approximately 8.2 days in the dog.
• Most osmotically active protein due to abundance and small size.

Sampling

Tests

Methodologies

• Colorimetric method based on binding to bromocresol green.
• Other dyes may result in more variable or erroneous values.

Availability

• Widely available.

Technique (intrinsic) limitations

• Only useful in conjunction with other laboratory and clinical findings.

Result Data

Further Reading

Publications

Referred papers

• Recent references from VetMedResource and PubMed.

Other sources of information

• Ettinger S J, Feldman E C & Cote E (2017) Eds. Textbook of Veterinary Internal Medicine. 8th edn. Elsevier, USA.
• Stockham S L, Scott M A (2002) Fundamentals of Veterinary Clinical Pathology. Iowa State Press, USA.
• Kaneko J J, Harvey J W & Brass M L (eds) (1997) Eds. Clinical Biochemistry of Domestic Animals. 5th edn. Academic Press, USA.
• Duncan J R, Prasse K W & Mahaffey E A (1994) Veterinary Laboratory Medicine. Clinical Pathology. 3rd edn. Iowa University Press, USA.