ISSN 2398-2942      

Toltrazuril

icanis
Contributor(s):

Vetstream Ltd

Andrea Tarr

Synonym(s): Anticoccidial


Introduction

Name

  • Toltrazuril. 

Class of drug

  • Triazinone antiprotozoal agent. 
  • Coccidiocide. 

Description

Chemical name

  • 1-methyl-3-[3-methyl-4-[4-(trifluoromethylsulfanyl)phenoxy]phenyl]-1,3,5-triazinane-2,4,6-trione.   

Molecular formula

  • C18H14F3N3O4S. 

Molecular weight

  • 425.38. 

Storage requirements

  • No special precautions for storage. 

Uses

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Indications

  • Used orally to treat intestinal and hepatic coccidiosis Coccidiosis (Isospora ohioensis complex Isospora ohioensis, Isospora canis Isospora canis) in dogs. Effective against the replication of Isospora and also against the shedding of oocysts. Although treatment will reduce the spread of infection, it will not be effective against the clinical signs of infection in already infected animals. 
  • Available in combination with the anthelmintic emodepside in the form of an oral suspension for use when there are mixed parasitic infections caused by roundworms and coccidia.  
  • Toltrazuril has been used for treating the oocyst shedding stage of toxoplasmosis in cats.

Administration

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Pharmacokinetics

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Precautions

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Adverse Reactions

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Further Reading

Publications

Refereed Papers

Other sources of information

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