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Mirtazapine
Synonym(s): Remeron®, Mirataz®, Zispin
Introduction
Name
- Mirtazapine.
Class of drug
- Tetracyclic antidepressant.
Description
Chemical name
- 1,2,3,4,10,14b-hexahydro-2-methylpyrazino [2,1-a] pyrido [2,3-c] benzazepine
Molecular formula
- C17H19N3
Molecular weight
- 265.36
Physical properties
- White to creamy white crystalline powder.
- Available as 15, 30 and 45 mg tablets (oral distintegrating) and 7.5, 15 and 30 mg tablets (scored film-coated).
Storage requirements
- The coated tablets and the orally disintegrating tablets should be stored at 25°C (77ºF) with excursions permitted to 15-30°C (59-86°F).
- Protect from light and moisture.
- The stability of the orally disintegrating tablets once removed from the tablet blister is unknown and immediate use is recommended.
Uses
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Administration
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Pharmacokinetics
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Precautions
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Withdrawal Periods
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Adverse Reactions
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Further Reading
Publications
Refereed Papers
- Recent references from VetMedResource and PubMed.
- Giorgi M, Yun H (2012) Pharmacokinetics of mirtazapine and its main metabolites in Beagle dogs: a pilot study. Vet J 192 (2), 239-241 PubMed.