Introduction

Name

• DOCP

Class of drug

• Mineralocorticoid hormone Adrenal: anatomy and physiology.

Description

Chemical name

• 21 (2,2-dimethyl-1-oxopropoxy)-pregn-4-ene-3,20-dione

Molecular formula

• C26 H38 O4

Molecular weight

• 414.58

Physical properties

• White odorless microcrystals.
• Stable in air.
• Soluble in methanol, ether and vegetable oils.

Storage requirements

• Store at room temperature, preferably 15 - 30 degrees C (59 - 86 degrees F).
• Protect from light.
• Protect from freezing.

Uses

Indications

• Adrenocortical insufficiency (Addison's disease) Hypoadrenocorticism.
  It is essential to accurately diagnose primary canine adrenocortical insufficiency before administration.

Administration

Precautions

Adverse Reactions

Further Reading

Publications

Refereed papers

• Recent references from PubMed and VetMedResource.
• MacCabe M D, Feldman E C, Lynn R C et al (1995) Subcutaneous Administration of Desoxycorticosterone Pivalate for the Treatment of Canine Hypoadrenocorticism. JAAHA 31 (2), 151-155 PubMed.
• Lynn R C, Feldman E C, Nelson R W (1993) Efficacy of Microcrystalline Desoxycorticosterone Pivalate for Treatment of Hypoadrenocorticism in Dogs. DOCP Clinical Study Group. JAVMA 202 (3), 392-396 PubMed.
• Lynn R C & Feldman E C (1991) Treatment of Canine Hypoadrenocorticism with Microcrystalline Desoxycorticosterone Pivalate. Br Vet J 147 (5), 478-483 PubMed.

Other sources of information

• www.percorten.com.