Introduction

Name

• Dimethylsulfoxide.

Class of drug

• Anti-inflammatory.

Uses

Indications

• Useful as a carrier to enhance absorption of other drugs through skin.
• Otitis externa Skin: otitis externa (topical anti-inflammatory).
• Management of hemorrhagic cystitis induced by cyclophosphamide Cyclophosphamide.
• To decrease intra-cranial pressure (IV use) following central nervous system (CNS) trauma Brain: trauma.
• Amyloidosis Amyloidosis (efficacy unproven).
• Management of reperfusion injury, eg following gastric/intestinal torsion Stomach: gastric dilatation / volvulus (GDV) syndrome (free radical scavenger).
• Must be administered prior to reperfusion to be effective.

Administration

Precautions

Adverse Reactions

Further Reading

Publications

Refereed papers

• Recent references from PubMed and VetMedResource.

Other sources of information

• Based on Small Animal Formulary. Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.