ISSN 2398-2942      

Digitoxin

icanis
Contributor(s):

Introduction

Name

  • Digitoxin.

Class of drug

  • Cardiac glycoside.

Description

Chemical name

  • (3-beta,5-beta)-3-[(O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-1(1 → 4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1 → 4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide.

Molecular formula

  • C41H64O13.

Physical properties

  • Tablets.

Uses

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Indications

Administration

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Precautions

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Interactions

with other drugs

Drugs inhibiting digitoxin absorption from gastrointestinal (GI) tract Drugs affecting digitoxin (increased serum level, decreased elimination rate or increased toxicity) Spironolactone
  • Spironolactone Spironolactone may enhance or decrease the toxic effects of digitoxin.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Based on Small Animal Formulary. Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.
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