Introduction

Name

• Cythioate.

Class of drug

• Organophosphorous cholinesterase inhibitor.

Description

Chemical name

• Phosphorothioic acidO-[4-(aminosulfonyl)phenyl]O,O-dimethyl ester.
• Phosphorothioic acidO,O-dimethyl esterO-ester +p-hydroxybenzenesulfonamide.

Molecular formula

• C8H12NO5PS2.

Physical properties

• Tablets.
• Solution.

Uses

Indications

• Fleas.
• Demodicosis.
• Ticks.

Administration

Precautions

Interactions

with other drugs

• Do not use different organophosphate compounds concomitantly as enhanced toxicity may develop Organophosphorus poisoning.
• Neuromuscular blockade will be enhanced by organophosphorus compounds.
• Do not use acepromazine or other phenothiazines within one month of worming with an organophosphate compound as their effects may be potentiated.

Adverse Reactions

Further Reading

Publications

Refereed papers

• Recent references from PubMed and VetMedResource.

Other sources of information

• Plumb D C (1999) Veterinary Drug Handbook. 3rd edn. Ames, Iowa: Iowa State University Press. pp 167-168.
• Based on Tennant B (1999) Small Animal Formulary. 3rd edn. Cheltenham: BSAVA. ISBN: 0 905214 44 7.