Introduction

Name

• Colchicine.

Class of drug

• Anti-inflammatory.

Description

Chemical name

• (S-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide.

Molecular formula

• C22H25NO6.

Physical properties

• Light yellow powder.
• Tablets.

Storage requirements

• Protect from light.

Uses

Indications

• Management of fibrotic hepatic and pulmonary diseases.
• Management of renal amyloidosis Amyloidosis.

Administration

Precautions

Interactions

with diagnostic tests

• May elevate serum alkaline phosphatase and ALT values.
• May decrease thrombocyte values.
• May cause false-positive results when testing urine for RBC's and Hb.

Adverse Reactions

Further Reading

Publications

Refereed papers

• Recent references from PubMed and VetMedResource.

Other sources of information

• Based on BSAVA Small Animal Formulary. Ramsey I (2017) 9th edn. Cheltenham: BSAVA.