Introduction

Name

• Cimicoxib.

Class of drug

• COX-2 inhibitor.

Description

Chemical name

• 4-[4-Chloro-5-(3-fluoro-4-methoxyphenyl)-1H-imidazol-1-yl]benzenesulfonamide.

Molecular formula

• C16H13ClFN3O3S

Storage requirements

• Keep put of reach of children.
• Cimicoxib can cause mild skin sensitization following skin contact, therefore wash hands after handling the drug.

Uses

Indications

• Treatment of pain associated with arthritis Arthritis: osteoarthritis in dogs.
• Management of peri-operative pain in orthopedic and soft-tissue procedures in dogs.

Administration

Precautions

Interactions

with other drugs

• Do not use together with non-steroidal anti-inflammatory drugs (NSAIDs) or corticosteroids, medicines commonly used in the treatment of pain, inflammation and allergies. Dogs and cats receiving ACE inhibitors and/or diuretics concurrently with cimicoxib should be monitored carefully for signs of hypotension that will increase the risk of renal side effects. NSAIDs have the potential to increase serum potassium concentration, moniotr potassium concentrations in dogs receiving supplemental potassium (for example as part of a management protocol of chronic kidney disease).

Adverse Reactions

Further Reading

Publications

Refereed papers

• Recent references from PubMed and VetMedResource.

Other sources of information

• EMA EPAR (2011) Cimalgex. European Public Assessment Report. London, UK.
• Vetoquinol Animal Health, supporting product literature: http://www.vetoquinol.co.uk/OurProducts/Datasheet/datasheet_cimalgex_v1_1.pdf.