Introduction

Name

• Chlorhexidine gluconate.

Class of drug

• Antiseptic.

Description

Chemical name

• N,N"-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetrazatetradecanediimidamide.
• 1,1'-hexamethylenebis[5-(p-chlorophenyl)biguanide].

Molecular formula

• C22H30Cl2N10.

Physical properties

• Pale yellow aqueous solution.

Storage requirements

• <25°C.

Uses

Indications

• Topical antiseptic/germicide.
• It is not inactivated by organic matter.

Administration

Adverse Reactions

Further Reading

Publications

Refereed papers

• Recent references from PubMed and VetMedResource.
• Lloyd D H, Lamport A I (1999) Activity of chlorhexidine shampoos in vitro against Staphylococcus intermedius, Pseudomonas aeruginosa and Malassezia pachdermatis. Vet Rec 144 (19), 536-537 PubMed.
• Bond R, Lloyd D H (1998) Effect of topical therapy of Malassezia pachydermatis-associated seborrhoeic dermatitis on oral carriage of M pachydermatis. Vet Rec 142 (26), 725-726 PubMed.
• Bond R, Rose J F, Ellis J W et al (1995) Comparison of two shampoos for treatment of Malassezia pachydermatis-associated seborrhoeic dermatitis in basset hounds. JSAP 36 (3), 99-104 PubMed.
• White-Weithers N, Medleau L (1995) Evaluation of topical therapies for the treatment of dermatophyte-infected hairs from dogs and cats. JAAHA 31 (3), 250-253 PubMed.

Other sources of information

• Tennant Bryn (1999) Small Animal Formulary. 3rd edn. Cheltenham: BSAVA. Source for all the above information.