Introduction

Name

• Cetrimide.

Class of drug

• Antiseptic agent.

Description

Chemical name

• Cetrimide is a mixture of tetradecyltrimethylammonium bromide with smaller amounts of dodecyltrimethylammonium bromide and cetrimonium bromide.
• N,N,N-Trimethyl-1-hexadecanaminium bromide.
• Hexadecyltrimethylammonium bromide.
• Cetyltrimethylammonium bromide.

Molecular formula

• C19H42BrN.

Molecular weight

• 364.45.

Physical properties

• Crystalline.

Uses

Indications

• Bacterial skin infections.
• Cleansing of contaminated wounds.

Administration

Precautions

Publications

Refereed papers

• Recent references from PubMed and VetMedResource.
• Langford J H, Benrimoj S (1997) Clinical investigation of topical antimicrobials in healthy volunteers. Ann Pharmacother 31 (1), 34-38 PubMed.
• O'Brien T J (1993) Cetrimide necrosis. Australas J Dermatol 34 (3), 118 PubMed.
• Czarnecki D, Meehan C, Nash C (1992) Prevention of post-excisional wound infections: a comparison of oral cephalexin with topical mupirocin and topical cetrimide-chlorhexidine cream. Int J Dermatol 31 (5), 359-360 PubMed.

Other sources of information

• Tennant B (1999) Small Animal Formulary. 3rd edn. British Small Animal Veterinary Association. ISBN 0 905214 52 8.