Introduction

Name

• Ceftazidime.

Class of drug

• Antibiotic.

Uses

Indications

• Good activity againstPseudomonasspp Pseudomonas aeruginosa.
• Use reserved for patients with acute sepsis or serious infections where cultures are pending and the animal is not a good candidate for intensive aminoglycoside therapy (pre-existing renal dysfunction).
• Cephalosporins are particularly useful for the treatment of susceptible renal infections.

Administration

Precautions

Interactions

with other drugs

Antibiotics

• The bactericidal activity of cephalosporins may be affected by the concomitant use of bacteriostatic agents (eg tetracycline Tetracycline , erythromycin Erythromycin ).
• There may be an increased risk of nephrotoxicity if cephalosporins are used with amphotericin or loop diuretics (eg frusemide Furosemide ); monitor renal function.
• Probenecid reduces the excretion of cephalosporins.

Publications

Refereed papers

• Recent references from PubMed and VetMedResource.

Other sources of information

• Based on Small Animal Formulary. Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA. ISBN: 0 905214 44 7.