Introduction

Name

• Cefadroxil.

Class of drug

• First generation cephalosporin antibiotic.

Uses

Indications

• Pasteurellaspp Pasteurella multocida ,Escherichia coli Escherichia coli , andStaphylococcusspp Staphylococcus spp.
• Cephalosporins are particularly useful for the treatment of susceptible renal infections.

Administration

Precautions

Interactions

with other drugs

• Bactericidal activity may be affected by the concomitant use of bacteriostatic agents (eg erythromycin Erythromycin , tetracycline Tetracycline ).
• Increased risk of nephrotoxicity if cephalosporins are used with amphotericin Amphotericin B or loop diuretics (eg frusemide Furosemide ); monitor renal function.
• Probenecid reduces the excretion of cephalosporins.

Adverse Reactions

Further Reading

Publications

Refereed papers

• Recent references from PubMed and VetMedResource.

Other sources of information

• Based on Small Animal Formulary. Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.