ISSN 2398-2942      

Capromorelin

icanis

Synonym(s): ENTYCE®


Introduction

Name

  • Capromorelin.

Class of drug

  • Selective ghrelin receptor agonist.

Description

Chemical name

  • 2-amino-N-[2-(3aR-benzyl-2-methyl-3-oxo-2,3,3a,4,6,7-hexahydro-pyrazolo[4,3-c]pyridin-5-yl)-1R-benzyloxymethyl-2-oxo-ethyl]-isobutyramide L-tartrate.

Molecular formula

  • C28H35N5O4·C4H6O6

Molecular weight

  • 655.70.

Physical properties

  • Oral solution.

Storage requirements

  • Store at or below 86°F (30°C).

Uses

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Indications

  • Inappetence in dogs.

Administration

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Rhodes L, Zollers B, Wofford J A et al (2017) Capomorelin: a ghrelin receptor agonist and novel therapy for stimulation of appetite in dogs. Vet Med Sci (1), 3-16 PubMed.
  • Zollers B, Rhodes L & Heinen E (2017) Capromorelin oral solution (ENTYCE®) increases food consumption and body weight when administered for 4 consecutive days to healthy adult Beagle dogs in a randomized, masked, placebo controlled study. BMC Vet Res 13 (1), 10 PubMed.
  • Zollers B, Wofford J A, Heinen E et al (2016) A Prospective, Randomized, Masked, Placebo-Controlled Clinical Study of Capromorelin in Dogs with Reduced Appetite. JVIM 30 (6), 1851-1857 PubMed.
  • Zollers B, Rhodes L, Smith R G (2016) Capromorelin increases food consumption, body weight, growth hormone, and sustained insulin-like growth factor 1 concentrations when administered to healthy adult Beagle dogs. J Vet Pharmacol Ther 40 (2), 140-147 PubMed.
  • Zollers B, Huebner M, Armintrout G et al (2016) Evaluation of the safety in dogs of long-term, daily oral administration of capromorelin (ENTYCE®), a novel drug for stimulation of appetite. J Vet Pharmacol Ther 40 (3), 248-255 PubMed.

Other sources of information

RELATED CONTENT

Anorexia

Want more related items, why not
contact us

MEMBER BENEFIT

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code