Introduction

Name

• Bromocriptine.

Class of drug

• Synthetic ergot alkaloid derivative.

Description

Physical properties

• Yellowish white powder - slightly soluble in water.

Uses

Indications

• Management of behavioral changes associated with pseudopregnancy Pseudopregnancy (false pregnancy or pseudocyesis).
• Suppression of lactation.
• Termination of pregnancy.
• Interruption of anestrus.
• Management of pituitary-dependent hyperadrenocorticism Hyperadrenocorticism.
• Efficacy is low and side-effects are common for this indication.
• ?Management of acromegaly Acromegaly.

Administration

Pharmacokinetics

Precautions

Interactions

with other drugs

• Drugs increasing prolactin concentrations eg amitriptyline and phenothiazines may necessitate increased doses of bromocriptine for prolactin suppression.
• Metoclopramide may antagonise its hypoprolactinemia affect.

Adverse Reactions

Further Reading

Publications

Refereed papers

• Recent references from PubMed and VetMedResource.