Introduction

Name

• Acetazolamide.

Class of drug

• Carbonic anhydrase inhibitor.

Description

Chemical name

• N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide.
• 5-acetamido-1,3,4-thiadiazole-2-sulfonamide.

Molecular formula

• C4H6N4O3S2.

Uses

Indications

• Episodic falling in the Cavalier King Charles spaniel Episodic falling (Cavalier King Charles Spaniel).

Administration

Precautions

Interactions

with other drugs

• Primidone Primidone absorption may be inhibited by oral acetazolamide.
• Acetazolamide alkalinizes urine, thus the excretion rate of weak bases may be decreased, but weak acids increased.
• With corticosteroids may increase potassium loss causing hypokalemia Hypokalemia.

Adverse Reactions

Further Reading

Publications

Refereed papers

• Recent references from PubMed and VetMedResource.

Other sources of information

• Ramsey I (2017) BSAVA Small Animal Formulary. 9th edn.