ISSN 2398-2942      

Therapeutics: gastrointestinal system

icanis

Introduction

  • This article will cover:
    • Antidiarrheal drugs.
    • Anti-emetics and emetics.
    • Laxatives.
    • Modulators of intestinal motility.
Drugs are included which may not be licensed for veterinary use in every country. 

Antidiarrheal Drugs

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Anti-emetics and emetics

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Laxatives

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Modulators of intestinal motility

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Marks S L, Kook P H, Papich M G, Tolbert M K, Willard M D (2018) ACVIM consensus statement: Support for rational administration of gastrointestinal protectants to dogs and cats. J Vet Intern Med 32(6), 1823-1840 PubMed
  • Annaházi A, Róka R,  Rosztóczy A, Wittmann T (2014) Role of antispasmodics in the treatment of irritable bowel syndrome. World J Gastroenterol 20(20), 6031-43 PubMed.
  • Bybee S N, Scorza A V, Lappin M R (2011) Effect of the probiotic Enterococcus faecium SF68 on presence of diarrhea in cats and dogs housed in an animal shelter. J Vet Intern Med 25(4), 856-860 PubMed
  • Le Traon G, Burgaud S, Horspool L J (2009) Pharmacokinetics of cimetidine in dogs after oral administration of cimetidine tablets. J Vet Pharmacol Ther 32 (3), 213-218 PubMed.
  • Narishetty S T, Galvan B, Coscarelli E et al (2009) Effect of refrigeration of the antiemetic Cerenia (maropitant) on pain on injection. Vet Ther 10 (3), 93-102 PubMed.
  • Brown A J, Otto C M (2008) Fluid therapy in vomiting and diarrhea. Vet Clin North Am Small Anim Pract 38 (3), 653-675, xiii PubMed.
  • Conder G A, Sedlacek H S, Boucher J F et al (2008) Efficacy and safety of maropitant, a selective neurokinin 1 receptor antagonist, in two randomized clinical trials for prevention of vomiting due to motion sickness in dogs. J Vet Pharmacol Ther 31 (6), 528-532 PubMed.
  • Ramsey D S, Kincaid K, Watkins J A et al (2008) Safety and efficacy of injectable and oral maropitant, a selective neurokinin 1 receptor antagonist, in a randomized clinical trial for treatment of vomiting in dogs. J Vet Pharmacol Ther 31 (6), 538-543 PubMed.
  • Sedlacek H S, Ramsey D S, Boucher J F et al (2008) Comparative efficacy of maropitant and selected drugs in preventing emesis induced by centrally or peripherally acting emetogens in dogs. J Vet Pharmacol Ther 31 (6), 533-537 PubMed.
  • Benchaoui H A, Siedek E M, De La Puente-Redondo V A et al (2007) Efficacy of maropitant for preventing vomiting associated with motion sickness in dogs. Vet Rec 161 (13), 444-447 PubMed.
  • de la Puente-Redondo V A, Siedek E M, Benchaoui H A et al (2007) The anti-emetic efficacy of maropitant (Cerenia) in the treatment of ongoing emesis caused by a wide range of underlying clinical aetiologies in canine patients in Europe. J Small Anim Pract 48 (2), 93-98 PubMed.
  • Vail D M, Rodabaugh H S, Conder G A et al (2007) Efficacy of injectable maropitant (Cerenia) in a randomized clinical trial for prevention and treatment of cisplatin-induced emesis in dogs presented as veterinary patients. Vet Comp Oncol (1), 38-46 PubMed.
  • Valverde A, Cantwell S, Hernández J et al (2004) Effects of acepromazine on the incidence of vomiting associated with opioid administration in dogs. Vet Anaesth Analg 31 (1), 40-45 PubMed.

Other sources of information

  • Suchodolski J (2020) Probiotics, Prebiotics, Synbiotics, and Intestinal Health of Dogs and Cats. Today's Vet Pract 10(4), 24-27 Full Article.  
  • Allerton F (Ed) BSAVA Small Animal Formulary. 10th edn. British Small Animal Veterinary Association, Quedgeley, Gloucester UK. 2010. 
  • Talcott P A (2012) Decontamination Procedures in Poisoned Companion Animals - Facts & Fiction. Western Veterinary Conference 2012; Washington State University, Pullman, WA, USA. 

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