Treat Canis Sweat gland: hyperplasia / neoplasia

Sweat gland: hyperplasia / neoplasia

i canis

Contributor(s):

David Godfrey

David Scarff

Synonym(s): Apocrine cyst, apocrine cystomatosis, apocrine nevus (hyperplasia, papillary syringoadenoma, cystadenoma of apocrine sweat gland, apocrine cystadenoma, apocrine adenoma(glandular, mixed or compound, ductular or basiloid, apocrine carcinoma (apocrine cystadenocarcinoma, mixed or compound, ductular, spiradenoma, mixed tumor of apocrine sweat gland, carcinoma of apocrinesweat gland, eccrine carcinoma

Introduction

Cause: unknown.
Signs: usually solitary raised skin masses.
Diagnosis: examination, cytology and histopathology.
Treatment: surgical excision.
Prognosis: excellent except for occasionally highly aggressive malignancies.

Pathogenesis

Etiology

Cysts are assumed to arise from blockage of the gland's duct.
The cause of benign and malignant neoplasms are unknown.

Predisposing factors

General

Increasing age.

Pathophysiology

There is a profusion of names that attempt to describe the specific origin of the neoplasm, as well as its behavior (see synonyms above).
But histopathology has not been shown to correlate well with biological behavior.
However the distinction between adenocarcinoma arising from epitrichial (hair-associated) glands and atrichial (eccrine) glands is important. The latter which are found only on the footpads are usually highly malignant.

Timecourse

Weeks to months.

Epidemiology

Seen in older dogs.

Diagnosis

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Treatment

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Prevention

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Outcomes

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Sweat gland: hyperplasia / neoplasia

Introduction