Introduction

• A chronic inflammatory disease of the stomach.
• Cause: rarely determined but may include dietary hypersensitivity or intolerance.
• Concurrent intestinal involvement may occur.
• Diagnosis: biopsy findings; exclusion of other causes of gastric inflammation.
• Treatment: hypoallergenic diet, prednisolone, anti-emetics; azathioprine in severe cases.
• Prognosis: generally good.

Pathogenesis

Etiology

• Majority of cases are described as idiopathic.
• Dietary hypersensitivity Skin: food hypersensitivity /food intolerance is thought to be important in some cases.
• Some cases have concurrentHelicobacterinfection Helicobacter spp - significance not known.

Predisposing factors

• None identified.

Pathophysiology

• An inflammatory reaction to an unknown stimulas results in the accumulation of lymphocytes and plasma cells within the lamina propria.
• Gastric lymphosarcoma Lymphoma may appear similar to lymphocytic plasmacytic gastritis in its early stages.

Timecourse

• Months.

Diagnosis

Treatment

Prevention

Outcomes