ISSN 2398-2969      

Nasal planum: squamous cell carcinoma

icanis

Synonym(s): SCC nasal planum


Introduction

  • Squamous cell carcinoma of the nasal planum is an uncommon tumor in dogs. Unlike cats it is not associated with a lack of pigmentation and exposure to UV irradiation.

Pathogenesis

Etiology

  • Multiple accumulated genetic errors lead to disordered cell growth.

Pathophysiology

  • A malignant tumor of keratinocytes, with slow invasive local growth and metastasis only late in disease that infrequently spreads beyond regional lymph nodes.
  • Resembles a crusting ulcer or minor wound. Local invasion leads to a thickened and indurated nature. Metastasis, however, is only late in disease, usually to regional lymph nodes and only very rarely to lungs.
  • Disease results from local destruction of tissues and interference with function, and secondary bacterial infection.

Timecourse

  • Months to years.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Lascelles B D, Henderson R A, Sequin B, Liptak J M & Withrow S J (2004) Bilateral rostral maxillectomy and nasal planectomy for large rostral maxillofacial neoplasms in six dogs and one cat. JAAHA 40 (2), 137-146 PubMed.
  • Lascelles B D, Parry A T, Stidworthy M F, Dobson J M & White R A (2000) Squamous cell carcinoma of the nasal planum in 17 dogs. Vet Rec 147 (17), 473-476 PubMed.
  • Rogers K S, Helman R G & Walker M A (1995) Squamous cell carcinoma of the canine nasal planum: eight cases (1988-1994). JAAHA 31 (5), 373-378 PubMed.
  • Kirpensteijn J, Withrow S J & Straw R C (1994) Combined resection of the nasal planum and premaxilla in three dogs. Vet Surg 23 (5), 341-346 PubMed.
  • Thrall D E & Adams W M (1982) Radiotherapy of squamous cell carcinomas of the canine nasal plane. Vet Radiol 23 (5), 193-196 VetMedResource.

Other sources of information

  • Meuten D J (2002)Tumors in Domestic Animals.4th Ed. Iowa State Press.

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