Introduction

• Rare, highly effusive tumor of epithelial lining of body cavities.
• Signs: hemorrhagic effusion, dyspnea, exercise intolerance, mediastinal mass.
• Diagnosis: radiography/ultrasonography, histopathology.
• Treatment: chemotherapy.
• Prognosis: guarded - some animals respond well to chemotherapy.

Pathogenesis

Etiology

• Exposure to asbestos?

Pathophysiology

• Neoplastic cells of epithelial lining of body cavities produce an effusion resulting in various symptoms dependent on site.
• Most common sites: pleura, pericardium, abdominal peritoneum, vaginal tunic of scrotum.

• Neoplastic epithelial cells → effusion → impingement on organs → abnormal function, eg dyspnea, exercise intolerance, vomiting.
• Neoplastic cells → mediastinal mass.

Diagnosis

Treatment

Prevention

Outcomes