Introduction

• Chronic, progressive, destructive inflammatory arthropathy, usually affecting several joints.
• Cause: immune-mediated arthropathy.
• Signs: stiffness and joint swelling.
• Diagnosis: radiography.
• Treatment: immunosuppressive therapy.
• Prognosis: guarded.

Pathogenesis

Etiology

• Immune complexes forming as a result of production of immunoglobulin M antibody against self immunoglobulin G.

Pathophysiology

Diagnosis

Treatment

Outcomes