ISSN 2398-2942      

Pneumocystis carinii

icanis
Contributor(s):

Ibulaimu Kakoma

Synonym(s): P. carinii


Introduction

Classification

Taxonomy

  • Phylum: Sarcomastigophora.
  • Subphylum: Sarcodina.
  • Genus: Pneumocystis.
  • Species: carinii.

Etymology

  • Greek: pneuma - wind, spirit, air; kustis - bladder.
  • Latin: carina - keel, ridge.

Active Forms

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Clinical Effects

Epidemiology

Habitat

  • Main habitat - mammalian respiratory tract.

Lifecycle

  • Direct lifecycle.
  • Evaluation of RNA sequences suggests that P. carinii may be more closely related to fungi than protozoa.
  • Multiplies in lungs when host becomes immunosuppressed.

Transmission

  • Usually from infected to susceptible animal within species.
  • Infected aerosol.

Pathological effects

  • Majority disease seen in immunocompromised patients, eg human AIDS patients.
  • Usually confined to lung; pneumonia associated with large numbers P. carinii in alveolar spaces.
  • Interstitial pneumonia associated with large numbers of P. carinii organisms in alveolar spaces.

Other Host Effects

  • Most infections latent or subclinical.

Control

Control via chemotherapies

  • Trimethroprim-sulfonamide Trimethoprim.
  • Pentamidine is used as a prophylactic aerosol in human beings.

Diagnosis

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Masur H (1992) Prevention and treatment of pneumocystis pneumonia. New England J Med 327 (26), 1853-1860 PubMed.
  • Farrow B R, Watson A D, Hartley W J et al (1972) Pneumocystis pneumonia in the dog. J Comparative Pathology 82 (4), 447-453 PubMed.

Other sources of information

  • Greene C E and Chandler F W (1990) Pneumocystosis. In: Infectious diseases of the Dog and Cat. Ed: C E Greene. Philadelphia: W B Saunders. pp 854-61.

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code