ISSN 2398-2942      

Aspergillus terreus

icanis
Contributor(s):

Richard Walker


Introduction

Classification

Taxonomy

  • Kingdom: Plant.
  • Phylum: Fungi.
  • Class: Amastigomycota.
  • Order: Eurotiales.
  • Genus: Aspergillus.
  • Species: Terreus.

Etymology

  • Latin: asperge - to sprinkle. Latin: terra - earth.

Active Forms

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Clinical Effects

Epidemiology

Habitat

  • Saprophyte present in soil, decaying vegetation and feedstuffs.

Lifecycle

  • Aspergillus moulds consist of septate hyphae and asexual fruiting structures borne on conidiophores.
  • Hyphal branches originate in a foot cell in the mycelium and end in an expanding vesicle.
  • This is covered by a layer of phialides from which chains of conidia (asexual reproductive units), arise.
  • Only mycelium is seen in tissues.

Transmission

  • Inhalation or ingestion from the environment.

Pathological effects

  • Disseminated aspergillosis in humans, usually in immunocompromised patients.
  • May be associated with deficiency in mucosal immunity (with genetic basis), in dogs.
  • Canine disseminated aspergillosis; multiple organ systems affected; commonly vertebral pain and discharging sinuses.

Other Host Effects

  • Usually harmless saphrophyte.

Control

Control via animal

  • Treatment of disseminated aspergillosis is rarely successful.

Control via chemotherapies

  • There is no established treatment for systemic aspergillosis. Amphotericin B, thiabendazole and ketoconazole Ketoconazole , have no effect on disease progression.
  • Itraconazole Itraconazole , appears to be the drug of choice and has produced remission in some cases. However, continuous maintenance therapy is required.

Other countermeasures

  • Animals usually terminally ill when presented, therefore treatment not effective.

Diagnosis

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Dallman M J, Dew T L, Tobias L et al (1992) Disseminated aspergillosis in a dog with diskospondylitis and neurologic defects. JAVMA 200 (4), 511-513 PubMed.
  • Day M J & Penhale W J (1988) Humoral immunity in disseminated Aspergillus terreus infection in the dog. Vet Microbiol 16 (3), 283-294 PubMed.
  • Neer T M (1988) Disseminated aspergillosis. Comp Cont Ed Pract Vet 10 (4), 465-468, 470-471 VetMedResource.

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code