ISSN 2398-2942      

Aspergillus fumigatus

icanis
Contributor(s):

Richard Walker


Introduction

Classification

Taxonomy

  • Kingdom: Fungi.
  • Division: Amastigomycota.
  • Order: Eurotiales.
  • Genus: Aspergillus.
  • Species: fumigatus.

Etymology

  • L: asperge - to sprinkle; fumus - smoke.

Active Forms

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Clinical Effects

Epidemiology

Habitat

  • Grows abundantly in decaying vegetation, sewage sludge, compost, decomposing wood chips, and mouldy hay.
  • A. fumigatus becomes predominant over competing microbes in fermented plant material.

Lifecycle

  • Aspergillus molds consist of septate hyphae and asexual fruiting bodies borne on conidiophores.
  • Conidiophore originates in a foot cell in the mycelium and ends in an expanding vesicle covered by a layer of phialides from which chains of conidia (asexual reproductive units) arise.
  • Only mycelium is seen in tissues.
  • Fruiting bodies can be seen in air sac infections in birds.

Transmission

  • Inhalation or ingestion from the environment.

Pathological effects

  • Depends on impaired defences in host to assume pathogenic role.
  • Produces hemolysins, proteolytic enzymes and other toxic factors but their role in pathogenesis is not known.
  • Horses: guttural pouch mycosis, nasal granulomas.
  • Dogs: otitis externa Skin: otitis externa (often mixed infection), chronic rhinitis (nasal aspergillosis Nasal aspergillosis/penicillosis).
  • Cattle: abortion, pneumonia, mastitis.
  • Birds: pneumonia and respiratory tract infection.
  • Humans: local infection, generalized infection and allergic reactions (often affects immunocompromised patients).
  • Cats: rare, pneumonia.

Other Host Effects

  • Opportunistic pathogen.

Control

Control via chemotherapies

Vaccination

  • Not available.

Diagnosis

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Sharp N J, Sullivan M, Harvey C E et al (1993) Treatment of canine nasal aspergillosis with enilconazole. JVIM (1), 40-43 PubMed.
  • Pavletic M M & Clark G N (1991) Open nasal cavity and frontal sinus treatment of chronic canine aspergillosis. Vet Surg 20 (1), 43-48 PubMed.
  • Sharp N H J, Harvey C E, Sullivan M (1991) Canine nasal aspergillosis and penicillinosis. Comp Cont Ed Pract Vet 13 (1), 41-46, 47 VetMedResource.

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code