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Trimethoprim/sulfamethoxazole
Synonym(s): Trimethoprim and sulfamethoxazole, TMP/SMX, Co-trimoxazole
Introduction
In the UK, trimethoprim/sulfamethoxazole is classified as category D (Prudence) by the European Medicines Agency (EMA).
Name
- Trimethoprim/sulfamethoxazole.
Class of drug
- Potentiated sulfonamide antimicrobial.
Description
Molecular formula
- C24H29N7O6S.
Molecular weight
- 543.599 g/mol.
Storage requirements
- Protect from light and store at room temperature (<25°C/77°F).
Uses
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Administration
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Pharmacokinetics
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Precautions
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Withdrawal Periods
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Adverse Reactions
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Shirani D, Selk Ghaffari M, Akbarein H et al (2010) Effects of short-term oral administration of trimethoprim-sulfamethoxazole on Schirmer II tear test results in clinically normal rabbits. Vet Rec 166 (20), 623-624 PubMed.
Other sources of information
- Meredith A (2015) BSAVA Small Animal Formulary. Part B: Exotic Pets. 9th edn. BSAVA, Quedgeley, Gloucester.
- European Medicines Agency (online) Categorisation of Antibiotics for Use in Animals for Prudent and Responsible Use. Website: www.ema.europa.eu (pdf download).