lapis - Articles
Benzylpenicillin
Synonym(s): Penicillin G, Penicillin G potassium, Benzylpenicillin potassium salt, Penicillin G sodium, Benzylpenicillin sodium salt
Introduction
In the UK, Benzylpenicillin is classified as category D (Prudence) by the European Medicines Agency (EMA).
Name
- Penicillin G.
Class of drug
- Penicillin antibiotic.
Description
Chemical name
- Sodium;(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate.
- Potassium;(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate.
Molecular formula
- Benzylpenicillin sodium: C16H17N2NaO4S.
- Benzylpenicillin potassium: C16H17KN2O4S.
Molecular weight
- Benzylpenicillin sodium: 356.37.
- Benzylpenicillin potassium: 372.48.
Physical properties
- Benzylpenicillin sodium: white/yellow crystalline powder with a slight odor.
- Benzylpenicillin potassium: liquid.
Uses
Subscribe To View
This article is available to subscribers.
Try a free trial today or contact us for more information.
Administration
Subscribe To View
This article is available to subscribers.
Try a free trial today or contact us for more information.
Pharmacokinetics
Subscribe To View
This article is available to subscribers.
Try a free trial today or contact us for more information.
Precautions
Subscribe To View
This article is available to subscribers.
Try a free trial today or contact us for more information.
Withdrawal Periods
Subscribe To View
This article is available to subscribers.
Try a free trial today or contact us for more information.
Adverse Reactions
Subscribe To View
This article is available to subscribers.
Try a free trial today or contact us for more information.
Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Jekl V, Hauptman K, Minarikova A et al (2016) Pharmacokinmetic study of benzylpenicillin potassium after intramuscular administration in rabbits. Vet Rec 179 (1), 18 PubMed.
- Ivey E & Morrisey J (2000) Therapeutics for rabbits. Vet Clin North Am Exotic Anim Pract 3 (1), 183-216 PubMed.
Other sources of information
- European Medicines Agency (online) Categorisation of Antibiotics for Use in Animals for Prudent and Responsible Use. Website: www.ema.europa.eu (pdf download).