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Blood biochemistry: lactate dehydrogenase
Synonym(s): LD, LDH, Serum LDH, SLDH
Overview
- May be divided into isoenzymes found principally in skeletal muscle, cardiac muscle, liver and red blood cells - not organ specific, but useful in assessment of tissue damage.
- Longer half-life than creatine kinase.
Uses
Alone
- Skeletal muscle damage.
- Cardiac muscle damage.
- Liver damage.
Sampling
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Tests
Methodologies
- Varies between laboratories (electrophoresis needed for LDH isoenymes).
Availability
- Widely available.
Technique intrinsic limitations
- Test results most useful when interpreted in conjunction with other laboratory results and clinical findings.
LDH without isoenzymes is so non-specific that it is rarely interpretively useful.
Result Data
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Meredith A & Rayment L (2000) Liver disease in rabbits. Sem Avian Exotic Pet Med 9 (3), 146-152.
- Benson K G & Paul-Murphy J (1999) Clinical pathology of the domestic rabbit: acquisition and interpretation of samples. Vet Clin North Am Exotic Anim Pract 2 (3), 539-552 PubMed.
Other sources of information
- Varga M (2014) Textbook of Rabbit Medicine. 2nd edn. Butterworth-Heinemann, Elsevier, UK.
- Wesche P (2014) Clinical Pathology. In: BSAVA Manual of Rabbit Medicine. Eds: Meredith A & Lord B. BSAVA, UK. pp 124-137.
- Saunders R A & Rees Davies R (2005) Notes on Rabbit Internal Medicine. Blackwells, UK.