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Blood biochemistry: cortisol
Synonym(s): Hydrocortisone
Overview
- Major glucocorticoid regulated by ACTH and secreted by the adrenal cortex.
- Adrenal gland disease (hyperplasia and neoplasia) in neutered rabbits is characterized by an increase in testosterone, not an increase in cortisol levels.
- Cushing's disease (hyperadrenocorticism) is not reported in pet rabbits.
- ACTH stimulation test not clinically used in rabbits.
Uses
Alone
- Limited diagnostic value alone.
Other points
- In tact rabbits generally have higher values than neutered rabbits.
Sampling
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Tests
Methodologies
- Radioimmunoassay (RIA).
- Fluorometric.
- Chemiluminescence (Immulite).
Availability
- Not widely used in rabbits.
- Limited commercial availability.
Result Data
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Further Reading
Publications
Refereed Papers
- Recent references from PubMed and VetMedResource.
- Fecteau K A et al (2007) Diagnostic endocrinology: blood steroid concentrations in neutered male and female rabbits. J Exot Pet Med 16 (4), 256-259 VetMedResource.
- Lennox A M & Chitty J (2006) Adrenal neoplasia and hyperplasia as a cause of hypertestosteronism in two rabbits. J Exot Pet Med 15 (1), 56-58 VetMedResource.
Other sources of information
- Lennox A M & Fecteau K A (2014) Endocrine Disease. In: Manual of Rabbit Medicine. Eds: Meredith A & Lord B. BSAVA. pp 274-276.
- Wesche P (2014) Clinical Pathology. In: Manual of Rabbit Medicine. Eds: Meredith A & Lord B. BSAVA. pp 124-137.
- Saunders R A & Rees Davies R (2005) Differential Diagnosis. In: Notes on Rabbit Internal Medicine. Blackwell Publishing, UK. pp 1-68.