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Blood biochemistry: chloride
Synonym(s): Cl
Overview
- Major inorganic anion, along with bicarbonate.
- Freely diffusible throughout extracellular fluid.
- Generally levels lower than in dogs due to higher organic anion load in rabbits.
- [Chloride] may change inversely with [bicarbonate], but is more related (directly) to sodium levels.
- [Chloride] follows [sodium] Blood biochemistry: sodium .
Uses
In combination
- Used to classify alkalosis and acidosis in conjunction with bicarbonate and sodium:
- If chloride is lost → alkalosis.
- If chloride is retained → acidosis.
- Sodium Blood biochemistry: sodium and chloride ions are the most osmotically active solutes in plasma.
- Measured in conjunction with other electrolytes, eg sodium Blood biochemistry: sodium and potassium Blood biochemistry: potassium where metabolic disturbances may be suspected, eg severe diarrhea.
Sampling
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Tests
Availability
- Widely available at commercial laboratories.
Technique intrinsic limitations
- Test results only significant in conjunction with other laboratory test results and clinical findings.
Result Data
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Benson K G & Paul-Murphy J (1999) Clinical pathology of the domestic rabbit: acquisition and interpretation of samples. Vet Clin North Am Exotic Anim Pract 2 (3), 539-552 PubMed.
Other sources of information
- Wesche P (2014) Clinical Pathology. In: BSAVA Manual of Rabbit Medicine. Eds: Meredith A & Lord B. BSAVA, UK. pp 124-137.
- Varga M (2014) Textbook of Rabbit Medicine. 2nd edn. Butterworth Heinemann Elsevier, UK.
- Ariaca M, Bonhevi C & Montesinos A (2013) Point of Care Blood Gas and Electrolyte Analysis in Rabbits. Vet Clin North Am Equine Pract 16, 175-196.