Blood biochemistry: aspartate aminotransferase
Synonym(s): AST, Serum AST, SAST, Glutamic oxalo-acetic transaminase, GOT, Serum GOT, SGOT
Overview
- Highest activity levels are in liver and skeletal muscle.
Uses
Alone
- Skeletal muscle damage.
- Liver damage (hepatocellular necrosis).
- Cardiac ischemia.
Other points
- ALT Blood biochemistry: alanine aminotransferase (SGPT, ALT) is better for investigation of liver disease.
Sampling
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Tests
Methodologies
- Method and normal range may vary between laboratories.
Availability
- Widely available.
Technique intrinsic limitations
- Results only significant when interpreted in conjunction with other laboratory tests and clinical findings.
Result Data
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Meredith A & Rayment L (2000) Liver disease in rabbits. Sem Avian Exotic Pet Med 9 (3), 146-152.
- Benson K G & Paul-Murphy J (1999) Clinical pathology of the domestic rabbit: acquisition and interpretation of samples. Vet Clin North Am Exotic Anim Pract 2 (3), 539-552 PubMed.
Other sources of information
- Varga M (2014) Textbook of Rabbit Medicine. 2nd edn. Butterworth Heinemann Elsevier, UK.
- Wesche P (2014) Clinical Pathology.I n: BSAVA Manual of Rabbit Medicine. Eds: Meredith A & Lord B. BSAVA, UK. pp 124-137.