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Blood biochemistry: alanine aminotransferase (SGPT, ALT)
Synonym(s): ALT, Serum ALT, SALT, Glutamic-pyruvic transaminase, GPT, Serum GPT, SGPT
Overview
- Released to serum after damage to, or proliferation of, hepatocytes.
- Little tissue specificity in the rabbit. Heart muscle has similar ALT activity to liver.
- However, do see significant elevations in ALT in conditions of hepatic damage and necrosis.
Uses
In combination
- Detection of liver damage.
Sampling
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Tests
Methodologies
- Varies between laboratories.
Availability
- Widely available.
Result Data
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Meredith A & Rayment L (2000) Liver disease in rabbits. Sem Avian Exotic Pet Med9(3), 146-152.
- Benson K G & Paul-Murphy J (1999) Clinical pathology of the domestic rabbit: acquisition and interpretation of samples. Vet Clin North Am Exotic Anim Pract 2 (3), 539-552 PubMed.
Other sources of information
- Varga M (2014) Textbook of Rabbit Medicine. 2nd edn. Butterworth Heinemann Elsevier, UK.
- Wesche P (2014) Clinical Pathology. In: BSAVA Manual of Rabbit Medicine. Eds: Meredith A & Lord B. pp 124-137. BSAVA, UK.
- Fudge A M (1999) Laboratory Medicine. Avian and Exotic Pets. W B Saunders Co. ISBN: 0721 676 790.