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Terbinafine

ISSN 2398-2969


Introduction

Name

  • Terbinafine.

Class of drug

  • Allylamine antifungal agent.

Description

Chemical name

  • (E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride.

Molecular formula

  • C21H26ClN.

Molecular weight

  • 327.9 g/mol.

Storage requirements

  • This medicinal product does not require any special storage conditions.

Uses

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Administration

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Pharmacokinetics

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Precautions

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Withdrawal Periods

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Adverse Reactions

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Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMedResource.
  • Hawkins M G (2014) Advances in exotic mammal clinical therapeutics. J Exotic Pet Med 23 (1), 39-49 VetMedReource.
  • Bourguet A, Guyonnet A, Donzel E et al (2014) Keratomycosis in a pet rabbit (Oryctolagus cuniculus) treated with topical 1% terbinafine ointment. Vet Ophthal 19 (6), 504-509 PubMed.
  • Keller K A (2012) Therapeutic review: terbinafine. J Exotic Pet Med 21, 181-185 ResearchGate.
  • Kirkpatrick W R, Vallor A C, McAtee R K et al (2005) Combination therapy with terbinafine and amphotericin B in a rabbit model of experimental invasive aspergillosis. Antimicrob Agents Chemother 49 (11), 4751-4753 PubMed.
  • Sorensen K N, Sobel R A, Clemons K V et al (2000) Comparative efficacies of terbinafine and fluconazole in treatment of experimental coccidioidal meningitis in a rabbit model. Antimicrob Agents Chemother 44 (11), 3087-3091 PubMed.

Other sources of information

  • Morrisey J K & Carpenter J W (2021) Appendix: Formulary. In: Ferrets, Rabbits and Rodents Clinical Medicine and Surgery. 4th edn. Eds: Quesenberry K E, Orcutt C J, Mans C & Carpenter J W. Elsevier, USA. pp 620-630.
  • Hedley J (2020) Ed. BSAVA Small Animal Formulary, Part B: Exotic Pets.  10th edn. BSAVA, UK.
  • PubChem (2015) Compound Summary Terbinafine Hydrochloride.  National Center for Biotechnology Information, USA. Website: www.pubchem.ncbi.nlm.nih.gov.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.