Amantadine in Cats (Felis) | Vetlexicon
felis - Articles

Amantadine

ISSN 2398-2950

Contributor(s) :


Introduction

Name

  • Amantadine. 

Class of drug

  • N-methyl-D-aspartate (NMDA)-receptor antagonist. 
  • Analgesic. 
  • Antiviral. 
  • Dopaminergic.

Description

Chemical name

  • Adamantan-1-amine. 

Molecular formula

  • C10H17N

Molecular weight

  • 151.25 

Physical properties

  • White, bitter-tasting crystalline powder.

Storage requirements

  • Tablets, capsules, and oral solution should be stored in tight light-resistant containers at room temperature 20°C-25°C. 
Print off the owner factsheet Medication: Amantadine to give to your client.

Uses

Subscribe To View

This article is available to subscribers.

Try a free trial today or contact us for more information.

Administration

Subscribe To View

This article is available to subscribers.

Try a free trial today or contact us for more information.

Pharmacokinetics

Subscribe To View

This article is available to subscribers.

Try a free trial today or contact us for more information.

Precautions

Subscribe To View

This article is available to subscribers.

Try a free trial today or contact us for more information.

Withdrawal Periods

Subscribe To View

This article is available to subscribers.

Try a free trial today or contact us for more information.

Adverse Reactions

Subscribe To View

This article is available to subscribers.

Try a free trial today or contact us for more information.

Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMedResource.
  • Shipley H, Flynn K, Tucker L et al (2021) Owner evaluation of quality of life and mobility in osteoarthritic cats treated with amantadine or placebo. J Feline Med Surg 23 (6), 568-574 PubMed
  • Norkus C, Rankin D, Warner M, KuKanich B (2015) Pharmacokinetics of oral amantadine in greyhound dogs. J Vet Pharmacol Ther 38(3), 305-308 PubMed.  
  • Madden M, Gurney M, Bright S (2014) Amantadine, an N-Methyl-D-Aspartate antagonist, for treatment of chronic neuropathic pain in a dog. Vet Anaesth Analg 41(4), 440-441 PubMed
  • KuKanich B (2013) Outpatient oral analgesics in dogs and cats beyond nonsteroidal antiinflammatory drugs: an evidence-based approach. Vet Clin Small Anim 43, 1109-1125 PubMed
  • Siao K T, Pypendop B H, Stanley S D, Ilkiw J E (2011) Pharmacokinetics of amantadine in cats. J Vet Pharmacol Ther 34(6), 599-604 PubMed
  • Bleidner W E, Harmon J B, Hewes W E, Lynes T E, Hermann E C (1965) Absorption, distribution and excretion of amantadine hydrochloride. J Pharmacol Exp Ther 150(3), 484-490 PubMed

Other sources of information

Organisation(s)

  • Type here